Lake Bisina is a freshwater lake in eastern Uganda. It is also known as Lake Salisbury connected upstream via a wetland to Lake Opeta and drains into Lake Kyoga.

Lake Bisina is one of Uganda’s 33 Important Bird Areas and since 2006 a Ramsar-listed wetland of international importance.

It is used as a feeding ground by wading birds, including the globally vulnerable Shoebill. The system is also important as a refuge for fish species that have gone extinct in the main Ugandan lakes such as Lakes Victoria and Kyoga.

Lake Bisina is most renowned for mud-fishing, birding activities.